Most land crops are highly optimized through seed banking and breeding programs, leading to efficient and productive cultivation. Aquaculture, on the other hand, and specifically the cultivation of seaweeds, lacks such advancements. Global seaweed production by 2026 is valued at approximately $23.2 billion underlying the worldwide growing interest in seaweeds as food and wide spectrum of bioactive compounds to be exploited. Because of loss of biodiversity and on-going perturbances of the marine ecosystems caused by global changes, and to assure future seaweed cultivation, a vital step for sustainability relates to germplasm readily available for cultivation, on-land or offshore. Germplasm through a seedbank approach is generally lacking for seaweeds, and the need to establish a reliable seed source while improving desired genotypes is crucial.